search_mechanism_failures — Approaches that failed for a mechanism (by target).
search_failed_replications — Findings that failed to replicate.
search_safety_failures — Clinical/preclinical safety failures across modalities.
search_target_history — ALL failed approaches against a target across every modality.
search_indication_history — ALL failed approaches for an indication across every modality.
search_pathogen_history — Vaccine + antimicrobial + antibody failures for a pathogen.
get_compound — A compound (structure, name, max clinical phase) + its full negative profile across modalities/sources.
get_finding_provenance — Full provenance + detail for a single finding by id.
get_target_landscape — Target 'graveyard' / exhaustion index: how many distinct compounds/agents have been tried against a target and failed, broken down by modality and outcome. Answ
list_top_targets — Coverage browse: the most heavily-pursued ('graveyard') targets, ranked by recorded negative findings. Optional family filter (kinase, gpcr, protease, nuclear_r
list_models — Summary of the Layer-1 inactivity-scoring model registry: how many per-target models, split by family, and median scaffold-split ROC-AUC.
get_model_card — Per-target Layer-1 model card: training counts and held-out scaffold-split metrics (ROC-AUC, PR-AUC, Brier, calibration). Accepts a gene symbol (e.g. EGFR) or U
get_coverage — Per-modality and per-source coverage stats (honest Phase-1 numbers).
Google Ads MCP server — manage campaigns, keywords, and metrics.