Model Context Protocol server for Gatan Microscopy Suite 3.60 — multimodal TEM/STEM/EELS/4D-STEM control via local LLMs
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# GMS-MCP 🔬 [](https://arxiv.org/abs/2025.XXXXX) [](https://github.com/NUANCE-IT/Gatan_MCP/actions/workflows/ci.yml) [](https://www.python.org/downloads/) [](LICENSE) [](https://github.com/astral-sh/ruff) [](https://www.nuance.northwestern.edu) > **A vendor-agnostic, privacy-preserving Model Context Protocol server for multimodal electron microscopy control via local large language models.** GMS-MCP connects **Gatan Microscopy Suite (GMS) 3.60** to any MCP-compatible LLM — running entirely on your institution's hardware, with zero cloud dependencies. --- ## Highlights | Capability | Details | |---|---| | Instrument API | Gatan DigitalMicrograph / GMS 3.60 | | LLM backend | Local Ollama (air-gap compatible) | | Voice control | Optional local push-to-talk + Whisper transcription | | Data handling | On-site, local-first workflow | | Modalities | TEM / HRTEM, STEM (HAADF/BF/ABF), 4D-STEM / NBED, EELS, diffraction | | Built-in analysis | Virtual BF/HAADF, CoM, DPC, radial profiles, max-FFT, filtering, maximum-spot mapping | | Automation | Stage control, beam/optics control, detector configuration, tilt series, persistent live-processing jobs | | Validation | Pydantic v2 physical-bound checks on tool inputs | | Simulation | Physics-plausible DMSimulator for hardware-free development | | Testing | 67-test suite (61 hardware-independent + 6 Ollama integration) | | Transport | stdio + Streamable HTTP + optional ZeroMQ live-job bridge | | License | MIT | --- ## Architecture ```…
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