MCP server for querying the NASA GeneLab Knowledge Graph with specialist tools for differential gene expression, DNA methylation, and organism abundance analyses (per-assay and cross-assay), plus DE/DM overlap detection, volcano and Venn plotting, session-scoped resource-based plot delivery, and AL…
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# MCP GeneLab Server [](https://opensource.org/licenses/BSD-3-Clause) [](https://www.python.org/downloads/) [](https://modelcontextprotocol.io/) [](https://pypi.org/project/mcp-genelab/) A Model Context Protocol (MCP) server that converts natural language queries into [Cypher](https://neo4j.com/product/cypher-graph-query-language) queries and executes them against the configured Neo4j endpoints. Customized tools provide seamless access to the NASA [GeneLab Knowledge Graph](https://github.com/BaranziniLab/spoke_genelab) (spoke-genelab v0.3.1), enabling AI-assisted analysis of spaceflight experiments and their biological effects. This server allows researchers to query differential gene expression, DNA methylation, and differential organism abundance data from NASA's space biology experiments through natural language interactions with AI assistants like Claude. The GeneLab Knowledge Graph integrates omics data from NASA's [Open Science Data Repository (OSDR)](https://science.nasa.gov/biological-physical/data/osdr/), with nodes that can be used as connectors to other knowledge graphs, such as the [SPOKE](https://spoke.ucsf.edu/) (Scalable Precision Medicine Open Knowledge Engine) knowledge graph. This integration connects spaceflight experimental results with a comprehensive biological context, including genes, proteins, anatomical structures, pathways, and diseases. This server is part of the NSF-funded [Proto-OKN Project](https://www.proto-okn.net/) (Prototype Open Knowledge Network). It's an extension of the [Neo4j Cypher MCP server](https://github.com/neo4j-contrib/mcp-neo4j/tree/main/servers/mcp-neo4j-cypher). ## Table of Contents - [Building and Querying the …
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