{"$schema":"https://wellknown.network/schemas/agent-record-v1.json","schemaVersion":"1","id":"ag_3mybaarkvz7j","handle":"refua-mcp","url":"https://wellknown.network/agents/refua-mcp","links":{"self":"https://wellknown.network/agents/refua-mcp/record.json","html":"https://wellknown.network/agents/refua-mcp","markdown":"https://wellknown.network/agents/refua-mcp/record.md","api":"https://wellknown.network/api/v1/agents/refua-mcp","status":"https://wellknown.network/api/v1/agents/refua-mcp/status","claim":"https://wellknown.network/agents/refua-mcp/claim","claimApi":"https://wellknown.network/api/v1/claims","claimDescriptor":"https://wellknown.network/agents/refua-mcp/claim.json","badge":"https://wellknown.network/agents/refua-mcp/badge.svg","openapi":"https://wellknown.network/openapi.json","history":"https://wellknown.network/api/v1/agents/refua-mcp/history","tools":"https://wellknown.network/api/v1/agents/refua-mcp/tools"},"ard":{"identifier":"urn:air::server:refua-mcp","type":"application/mcp-server-card+json"},"kind":"mcp_server","declared":{"name":"refua-mcp","summary":"MCP server for Refua design, data, clinical, wet-lab, benchmark, regulatory, and deployment workflows.","description":"# Refua MCP Server\n\nMCP server exposing strict, typed Refua tools for Boltz2 folding/affinity and BoltzGen design workflows.\n\nProtocol target: MCP spec revision `2025-11-25`.\n\n## Install\n\n```bash\npip install refua[cuda] # remove [cuda] if you don't need gpu support\npip install refua-mcp\n```\n\nADMET predictions are optional; install `refua[admet]` to enable them:\n\n```bash\npip install refua[admet]\n```\n\nClinical trial simulation is optional; install the clinical extra:\n\n```bash\npip install \"refua-mcp[clinical]\"\n```\n\nData catalog/query/source-validation tools are optional; install the data extra:\n\n```bash\npip install \"refua-mcp[data]\"\n```\n\nPreclinical planning/scheduling/bioanalysis/CMC tools are optional; install the preclinical extra:\n\n```bash\npip install \"refua-mcp[preclinical]\"\n```\n\nWetLab, benchmark, regulatory, and deployment tools are optional:\n\n```bash\npip install \"refua-mcp[wetlab,bench,regulatory,deploy]\"\n```\n\nInstall the full project tool surface with:\n\n```bash\npip install \"refua-mcp[ecosystem]\"\n```\n\nOpenTelemetry spans/metrics are optional:\n\n```bash\npip install \"refua-mcp[observability]\"\n```\n\nBoltz2 and BoltzGen require model/molecule assets. If you don't have them, refua can download them for you automatically:\n\n```bash\npython -c \"from refua import download_assets; download_assets()\"\n```\n\n- Boltz2: uses `~/.boltz` by default. Override via tool `boltz.cache_dir` if needed.\n- BoltzGen: uses the bundled HF artifact by default. Override via tool `boltzgen.mol_dir` if needed.\n\n## MCP Clients\n\n### Claude Code\n\nAdd the server to your Claude Code MCP config (macOS: `~/Library/Application Support/Claude/claude_code_config.json`, Linux: `~/.config/claude/claude_code_config.json`). This uses the default assets (`~/.boltz` for Boltz2 and the bundled BoltzGen artifact). Merge with any existing `mcpServers` entries:\n\n```json\n{\n  \"mcpServers\": {\n    \"refua-mcp\": {\n      \"command\": \"python3\",\n      \"args\": [\"-m\", \"refua_mcp.server\"]\n    }\n  }\n}\n```\n\n### Codex\n\nRegister the…","publisher":null,"homepage":"https://agentcures.com/","repository":"https://github.com/agentcures/refua-mcp","version":"0.8.0","license":null,"protocols":["mcp"],"tags":["drug","discovery","machine","learning","protein","design","structure","prediction","generative","mcp","ai","agent"],"pricing":null,"endpoints":[{"url":"pypi:refua-mcp","type":"package_pypi","auth":null,"probeable":false}],"skills":null,"tools":null,"extra":null,"attribution":{"kind":"pypi","name":"pypi","repoUrl":"pypi","summary":"pypi","version":"pypi","description":"pypi","homepageUrl":"pypi"}},"derived":{"capabilities":[{"slug":"media.3d","name":"3D & Design","confidence":1,"provenance":"declared"},{"slug":"dev.ci-cd","name":"CI/CD & Deploy","confidence":0.825,"provenance":"derived"}],"categories":["dev","media"],"language":"en"},"observed":{"status":"unknown","statusReason":"Distributed as a package to run locally; no network endpoint to check.","lastOkAt":null,"lastProbedAt":null,"statusComputedAt":null,"reliability30d":null,"latestObservations":[],"tools":null,"package":{"name":"refua-mcp","registry":"pypi","observedAt":"2026-11-03T23:22:56.624Z","publishedAt":"2026-05-08T05:17:10.233199Z","latestVersion":"0.8.0"},"toolSurface":null,"endpointFacts":[]},"verification":{"claimed":false,"claimedAt":null,"proofs":[]},"provenance":{"sources":[{"source":"pypi","key":"refua-mcp","url":"https://pypi.org/project/refua-mcp/","firstSeenAt":"2026-09-10T11:26:34.819Z","fetchedAt":"2026-11-03T23:21:42.023Z","normalizedAt":"2026-11-03T23:21:42.023Z"}]},"firstSeenAt":"2026-09-10T11:26:34.819Z","updatedAt":"2026-11-03T23:22:56.624Z"}